PhD Annual Seminar series

Seminars A.Y. 2024-2025

October 30, 2024 16:00: Prof. Linda Greensmith (UCL- London- UK)- Development of a novel therapeutic agent in models of ALS: challenges of translational neuroscience

November 7, 2024 14:00 Dr. Malanie Paillard ( INSERM researcher at CarMeN Laboratory)- "JOURNEYS INTO THE HEART DELVING DEEP INTO CARDIOVASCULAR PHYSIOLOGY AND PATHOPHYSIOLOGY" series- Cardiac Mitochondrial Ca2+ regulation: players, tools and physiopathological roles

November 15, 2024 16:00 Prof. Dr. Achim Paululat (Head of the Department of Zoology & Developmental Biology at the University of Osnabrück -Germany) -"JOURNEYS INTO THE HEART DELVING DEEP INTO CARDIOVASCULAR PHYSIOLOGY AND PATHOPHYSIOLOGY" series- Heart failure in flies and humans: A Drosophila model for human cardiomyopathies

February 7, 2025 16:00 Prof. José Antonio Enríquez Domínguez (Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain; CIBER de Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain.)-"JOURNEYS INTO THE HEART DELVING DEEP INTO CARDIOVASCULAR PHYSIOLOGY AND PATHOPHYSIOLOGY" series- OXPHOS structural heterogeneity in healthy heart mitochondria

March 7, 2025, Padua Mitochondria Lecture Series TITLE TBD 16:00 Prof. Laura Zelarayán (Department of Pharmacology and Toxicology at the University of Göttingen), "JOURNEYS INTO THE HEART DELVING DEEP INTO CARDIOVASCULAR PHYSIOLOGY AND PATHOPHYSIOLOGY" series- CRISPRa & Gene Regulation in the Heart

March 20, 2025 16:00 Prof. Laura Formentini (NIH)Padua Mitochondria Lecture Series TITLE TBD

February 26, 2025 16:00 Prof. Rüdiger Rudolf (Mannheim University of Applied Sciences) TITLE TBD

April 9, 2025 16:00 Dr. Dario Bonanomi (IRCCS San Raffaele Scientific Institute), Neurovascular crosstalk in nerve repair and degeneration

April 14, 2025 16:00 Prof. Helen Blau (Stanford University School of Medicine), Targeting a gerozyme to improve muscle regeneration and function in aging

April 17, 2025 Jean Emmanuel Sarry (INSERM, Cancer Research Center of Toulouse) Padua Mitochondria Lecture Series TITLE TBD

May 7, 2025 16:00 Prof. Manuela Basso (Università degli Studi di Trento) TITLE TBD

May 22, 2025 16:00 Prof. Daniela Carnevale (Università Sapienza di Roma)"JOURNEYS INTO THE HEART DELVING DEEP INTO CARDIOVASCULAR PHYSIOLOGY AND PATHOPHYSIOLOGY" series- Neural circuits controlling the immune responses involved in cardiovascular disease

May 29, 2025 16:00 Prof. Sandra Trifunovic (CECAD Cologne) Padua Mitochondria Lecture Series TITLE TBD

June 6, 2025 16:00 Prof. Yan Burelle (University of Ottawa) TITLE TBD

June 2025 Matteo Caleo Memorial TBD

July 17, 2025 16:00Dr. Rueben Shaw (Cancer Institute-Designated Cancer Center - Salk Institute for Biological Studies) Padua Mitochondria Lecture Series TITLE TBD

September 16, 2025 12:00 Prof. Nigel W. Bunnet (University of Calgary), TITLE TBD

September 25, 2025 16:00 Prof. Sofia Ahola (Univeristy of Birmingham) Padua Mitochondria Lecture Series TITLE TBD

October 23, 2025 Dr. Fabiana Perocchi (Technische Universität München) Padua Mitochondria Lecture Series TITLE TBD

November 20, 2025 16:00 Dr. Alessandra Boletta (HSR Research Ospedale San Raffaele) Padua Mitochondria Lecture Series TITLE TBD

December 12, 2025 16:00 Aleksandra Filipovska (University of Western Australia)-Padua Mitochondria Lecture Series TITLE TBD

October 24, 2024 16:00: Prof. Gerald S. Shadel, Ph.D. (Salk Institute for Biological Studies, Audrey Geisel Chair in Biomedical Science, Director, San Diego-Nathan Shock Center of Excellence in the Basic Biology of Aging), Padua Mitochondria Lecture Series- Mitochondrial Stress Signaling in Disease, Aging and ImmunityOctober 30, 2024 16:00: Prof. Linda Greensmith (UCL- London- UK)- Development of a novel therapeutic agent in models of ALS: challenges of translational neuroscienceNovember 7, 2024 14:00 Dr. Malanie Paillard ( INSERM researcher at CarMeN Laboratory)- "JOURNEYS INTO THE HEART DELVING DEEP INTO CARDIOVASCULAR PHYSIOLOGY AND PATHOPHYSIOLOGY" series- Cardiac Mitochondrial Ca2+ regulation: players, tools and physiopathological rolesNovember 15, 2024 16:00 Prof. Dr. Achim Paululat (Head of the Department of Zoology & Developmental Biology at the University of Osnabrück -Germany) -"JOURNEYS INTO THE HEART DELVING DEEP INTO CARDIOVASCULAR PHYSIOLOGY AND PATHOPHYSIOLOGY" series- Heart failure in flies and humans: A Drosophila model for human cardiomyopathiesFebruary 7, 2025 16:00 Prof. José Antonio Enríquez Domínguez (Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain; CIBER de Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain.)-"JOURNEYS INTO THE HEART DELVING DEEP INTO CARDIOVASCULAR PHYSIOLOGY AND PATHOPHYSIOLOGY" series- OXPHOS structural heterogeneity in healthy heart mitochondriaMarch 7, 2025, Padua Mitochondria Lecture Series TITLE TBD 16:00 Prof. Laura Zelarayán (Department of Pharmacology and Toxicology at the University of Göttingen), "JOURNEYS INTO THE HEART DELVING DEEP INTO CARDIOVASCULAR PHYSIOLOGY AND PATHOPHYSIOLOGY" series- CRISPRa & Gene Regulation in the HeartMarch 20, 2025 16:00 Prof. Laura Formentini (NIH)Padua Mitochondria Lecture Series TITLE TBDFebruary 26, 2025 16:00 Prof. Rüdiger Rudolf (Mannheim University of Applied Sciences) TITLE TBDApril 9, 2025 16:00 Dr. Dario Bonanomi (IRCCS San Raffaele Scientific Institute), Neurovascular crosstalk in nerve repair and degenerationApril 14, 2025 16:00 Prof. Helen Blau (Stanford University School of Medicine), Targeting a gerozyme to improve muscle regeneration and function in agingApril 17, 2025 Jean Emmanuel Sarry (INSERM, Cancer Research Center of Toulouse) Padua Mitochondria Lecture Series TITLE TBDMay 7, 2025 16:00 Prof. Manuela Basso (Università degli Studi di Trento) TITLE TBDMay 22, 2025 16:00 Prof. Daniela Carnevale (Università Sapienza di Roma)"JOURNEYS INTO THE HEART DELVING DEEP INTO CARDIOVASCULAR PHYSIOLOGY AND PATHOPHYSIOLOGY" series- Neural circuits controlling the immune responses involved in cardiovascular diseaseMay 29, 2025 16:00 Prof. Sandra Trifunovic (CECAD Cologne) Padua Mitochondria Lecture Series TITLE TBDJune 6, 2025 16:00 Prof. Yan Burelle (University of Ottawa) TITLE TBDJune 2025 Matteo Caleo Memorial TBDJuly 17, 2025 16:00Dr. Rueben Shaw (Cancer Institute-Designated Cancer Center - Salk Institute for Biological Studies) Padua Mitochondria Lecture Series TITLE TBDSeptember 16, 2025 12:00 Prof. Nigel W. Bunnet (University of Calgary), TITLE TBDSeptember 25, 2025 16:00 Prof. Sofia Ahola (Univeristy of Birmingham) Padua Mitochondria Lecture Series TITLE TBDOctober 23, 2025 Dr. Fabiana Perocchi (Technische Universität München) Padua Mitochondria Lecture Series TITLE TBDNovember 20, 2025 16:00 Dr. Alessandra Boletta (HSR Research Ospedale San Raffaele) Padua Mitochondria Lecture Series TITLE TBDDecember 12, 2025 16:00 Aleksandra Filipovska (University of Western Australia)-Padua Mitochondria Lecture Series TITLE TBD

Seminars A.Y. 2023-2024

October 26, 2023 16:00: Dr Maria Mittelbrunn (Severo Ochoa Research Center, Madrid, Spain), Padua Mitochondria Lecture Series- T cell metabolism at the crossroad between inflammation and aging

November 23rd, 2023 16:00: Prof. Isha Jain (University of California, San Francisco, USA) Turning the Oxygen and Vitamin Dials

February 24, 2024 16:00: Prof. Vincenzo Nigro (Università degli Studi di Napoli), Diagnosticare lo sconosciuto

February 24, 2024 17:00: Prof. Francesco Saverio Tedesco (University College London) Il malato in provetta

March 28, 2024 17:00: Dr. Nektarios Tavernarakis (Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas), Padua Mitochondria Lecture Series – Regulation of ageing by mitochondria-associated mRNA storage and degradation

April 18, 2024 16:00: Dr. Alessia Indrieri (Telethon Institute of Genetics Medicine (TIGEM), Pozzuoli, Italy) Padua Mitochondria Lecture Series – Exploring microRNA Modulation as a Novel Therapeutic Approach for Neurodegenerative Disorders Associated with Mitochondrial Dysfunction

May 9, 2024 17:00: Prof. Albert La Spada (University of California, Irvine) - Novel molecular mechanisms of spinocerebellar ataxia type 7 and ALS neurodegeneration

May 23, 2024 16:00: Eija Pirinen (Biomedicine and Internal Medicine Research Unit, University of Helsinki, Finland) Padua Mitochondria Lecture Series -In vitro model of human subcutaneous adipocyte spheroids for studying mitochondrial dysfunction and mitochondria activating compounds

June 12, 2024 16:00 Prof. Silvestro Micera (The BioRobotics Institute, Interdisciplinary Health Center, and Department of Excellence in Robotics and AI, Scuola Superiore Sant'Anna Bertarelli Foundation Chair in Translational Neuroengineering Neuro-X Institute, School of Engineering Ecole Polytechnique Federale de Lausanne)-Implantable and wearable systems to restore and augment neural functions

June 20, 2024 16:00: Dr. Sara Sigismund (Istituto Europeo Oncologico) Padua Mitochondria Lecture Series- Regulation of growth factor signalling via membrane contact sites

July 11, 2024 16:00: Prof. Ed Chouchani (Harvard Medical School, Dana-Farber Cancer Institute, Boston, USA) Padua Mitochondria Lecture Series- Mechanisms of metabolite regulation of protein function

September 19, 2024 16:00: Dr. Laura Greaves (Wellcome Centre for Mitochondrial Research, Biosciences Institute, Newcastle University), Padua Mitochondria Lecture Series- Mitochondrial DNA mutations in cancer – passive bystanders or active participants?

September 30, 2024 16:00: Prof. Leonid Margolis (Tbilisi Ilia State University, Georgia), - Extracellular vesicles - main mediators of cell-cell communications: More data than knowledge; Prof. Ron Kopito (Stanford University) - How the tiny, obscure, ubiquitin-like protein UFM1 orchestrates protein homeostasis

October 26, 2023 16:00: Dr Maria Mittelbrunn (Severo Ochoa Research Center, Madrid, Spain), Padua Mitochondria Lecture Series- T cell metabolism at the crossroad between inflammation and aging November 23rd, 2023 16:00: Prof. Isha Jain (University of California, San Francisco, USA) Turning the Oxygen and Vitamin Dials February 24, 2024 16:00: Prof. Vincenzo Nigro (Università degli Studi di Napoli), Diagnosticare lo sconosciuto February 24, 2024 17:00: Prof. Francesco Saverio Tedesco (University College London) Il malato in provetta March 28, 2024 17:00: Dr. Nektarios Tavernarakis (Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas), Padua Mitochondria Lecture Series – Regulation of ageing by mitochondria-associated mRNA storage and degradationApril 18, 2024 16:00: Dr. Alessia Indrieri (Telethon Institute of Genetics Medicine (TIGEM), Pozzuoli, Italy) Padua Mitochondria Lecture Series – Exploring microRNA Modulation as a Novel Therapeutic Approach for Neurodegenerative Disorders Associated with Mitochondrial Dysfunction May 9, 2024 17:00: Prof. Albert La Spada (University of California, Irvine) - Novel molecular mechanisms of spinocerebellar ataxia type 7 and ALS neurodegenerationMay 23, 2024 16:00: Eija Pirinen (Biomedicine and Internal Medicine Research Unit, University of Helsinki, Finland) Padua Mitochondria Lecture Series -In vitro model of human subcutaneous adipocyte spheroids for studying mitochondrial dysfunction and mitochondria activating compoundsJune 12, 2024 16:00 Prof. Silvestro Micera (The BioRobotics Institute, Interdisciplinary Health Center, and Department of Excellence in Robotics and AI, Scuola Superiore Sant'Anna Bertarelli Foundation Chair in Translational Neuroengineering Neuro-X Institute, School of Engineering Ecole Polytechnique Federale de Lausanne)-Implantable and wearable systems to restore and augment neural functionsJune 20, 2024 16:00: Dr. Sara Sigismund (Istituto Europeo Oncologico) Padua Mitochondria Lecture Series- Regulation of growth factor signalling via membrane contact sitesJuly 11, 2024 16:00: Prof. Ed Chouchani (Harvard Medical School, Dana-Farber Cancer Institute, Boston, USA) Padua Mitochondria Lecture Series- Mechanisms of metabolite regulation of protein functionSeptember 19, 2024 16:00: Dr. Laura Greaves (Wellcome Centre for Mitochondrial Research, Biosciences Institute, Newcastle University), Padua Mitochondria Lecture Series- Mitochondrial DNA mutations in cancer – passive bystanders or active participants?September 30, 2024 16:00: Prof. Leonid Margolis (Tbilisi Ilia State University, Georgia), - Extracellular vesicles - main mediators of cell-cell communications: More data than knowledge; Prof. Ron Kopito (Stanford University) - How the tiny, obscure, ubiquitin-like protein UFM1 orchestrates protein homeostasis

Seminars A.Y. 2022-2023

January 27, 2023 16:00 Prof. Thomas Langer (Max Planck Institute for Biology and Aging), Proteolytic programming of mitochondria in ageing and diseases

February 2, 2023 16:00: Prof. Leonid B. Margolis (Head of the Section of Intercellular Interactions - National Institutes of Health, Bethesda MD) The Padova Lecture Series 2023- Extracellular vesicles and viruses: Close relatives or mortal enemies?

February 10, 2023 14:00: Nika Danial, Atan Gross, Navdeep Chandel, Jared Rutter, Luca Pellegrini, Gyorgy Hajnoczky - Minisymposium Mitochondria in Health and disease

February 15, 2023 16:00: Dr. Rémi Mounier (Centre de Génétique et de Physiologie Moléculaires et Cellulaires-Université Claude Bernard- Lyon, France), Extracellular vesicles and viruses: Close relatives or mortal enemies

February 22, 2023 14:00: Dr. Arduino Arduini (Iperboreal Pharma Srl), Coupling glycolysis with Krebs cycle inhibits peritoneal fibrosis

February 23, 2023 16:00: Dr. Albert Quintana (Universitat Autònoma de Barcelona), Padova Lecture Series 2023- A pathogen from within: Cellular antiviral responses as a mechanism for neuropathology in mitochondrial disease

March 7, 2023 16:00: Prof. Marianna Patrauchan (Istituto di icrobiologia della Oklahoma University), A Novel Calcium Sensor EfhP Responds to ROS and Controls Iron Uptake in a Human Pathogen P. aeruginosa

March 9, 2023 17:00: Dott. Giuseppe Fiermonte 9 Marzo (University of Bari), Mitochondrial Uncoupling Protein 2 (UCP2): a master regulator of cell metabolic reprogramming

March 22, 2023 15:00: Prof. Charlotte Helfrich-Förster (Neurobiology and Genetics, Biocentre, Julius-Maximilians University of Wurzburg, Germany), Synchronisation Between Menstrual Cycles and the Luminance and Gravimetric Cycles of the Moon

March 23, 2023 17:00, Prof. Patrick Chinnery (University of Cambridge, UK), The Padova Lecture Series 2023- Why does mitochondrial dysfunction target specific cell types?

April 20, 2023: Derek Narendra (NINDS-NIH, Bethesda, USA), The Padova Lecture Series 2023- Curbing mitochondrial dysfunction in neurodegeneration: lessons from neurogenetics

April 17, 2023 15:00: Prof. Angelo D’Alessandro (Director of the Metabolomics Core of the School of Medicine; Director of the Mass Spectrometry Cancer Center Shared Resource - University of Colorado - Anschutz Medical Campus), Small molecules, big data and something in between: High-throughput Metabolomics, towards Personalized Transfusion Medicine

May 3, 2023 16:30: Dr. Roberto Feuda (Royal Society Research Fellow, Department of Genetics and Genome Biology-University of Leicester, UK) The origin and evolution of monoaminergic neurons

May 5, 2023: Nuno Raimundo (Penn State College of Medicine), The Padova Lecture Series 2023- Organelle networks: a mitochondria-centric perspective

July 6, 2023 16:00: Alessandro Prigione (Heinrich-Heine-University, Düsseldorf), The Padova Lecture Series 2023- Pluripotent stem cells and brain organoids for mitochondrial disease research

May 24, 2023 14:30: Prof. Andreas Daiber (Department/Division: Center for Cardiology - Cardiology 1, Institution: University Medical Center Mainz) Nitric oxide and superoxide – the Yin and Yang of the cardiovascular system

June 7, 2023 17:00: Prof. Michela Matteoli (CNR Institute of Neuroscience and Humanitas Research Hospital), How the immune system affects the synapse

June 16, 2023 12:00: Dr Elena Monti (Post Doctoral Research Scholar at Helen Blau's Laboratory, Department of Microbiology and Immunology, Faculty of Medicine, University of Stanford, USA) Targeting 15-PGDH to promote muscle rejuvenation

June 22, 2023 16:00: Prof. David Bishop (Institute for Health and Sport (iHeS), Victoria University, Australia), Divergent whole-muscle and fibre-type-specific mitochondrial remodelling to different exercise intensities in humans

June 26, 2023 16:30: Prof. Pietro Faccioli (“G. Occhialini“ Department of Physics ,University Milan-Bicocca and INFN Milan) and Prof. Emiliano Biasini (Dipartimento di Biologia Cellulare, Computazionale e Integrata CIBIO, Università di Trento), Functional, pathogenic, and pharmacological roles of protein folding intermediates

July 10, 2023, 10:30: Prof. Helen Miranda (State University of Londrina in Brazil), Development of a new human in vitro model to study neuromuscular diseases

September 28th, 2023 16:00: Dr. Matteo Bergami (CECAD Research Center, Cologne, Germany), The Padova Lecture Series 2023- Mitochondrial dynamics in neuronal plasticity

October 27, 2023: Dr. Luca Peruzzotti-Jametti (University of Cambridge) Metabolic control of myeloid cell function in chronic central nervous system inflammation

October 4, 2022, 17:00: Dott.ssa Cristina Ugalde (Instituto de Investigación Hospital 12 de Octubre, Madrid Centro de Investigación Biomédica en Red de Enfermedades Raras -CIBERER), Structural heterogeneity of the human respiratory chain January 27, 2023 16:00 Prof. Thomas Langer (Max Planck Institute for Biology and Aging), Proteolytic programming of mitochondria in ageing and diseasesFebruary 2, 2023 16:00: Prof. Leonid B. Margolis (Head of the Section of Intercellular Interactions - National Institutes of Health, Bethesda MD) The Padova Lecture Series 2023- Extracellular vesicles and viruses: Close relatives or mortal enemies? February 10, 2023 14:00: Nika Danial, Atan Gross, Navdeep Chandel, Jared Rutter, Luca Pellegrini, Gyorgy Hajnoczky - Minisymposium Mitochondria in Health and disease February 15, 2023 16:00: Dr. Rémi Mounier (Centre de Génétique et de Physiologie Moléculaires et Cellulaires-Université Claude Bernard- Lyon, France), Extracellular vesicles and viruses: Close relatives or mortal enemies February 22, 2023 14:00: Dr. Arduino Arduini (Iperboreal Pharma Srl), Coupling glycolysis with Krebs cycle inhibits peritoneal fibrosis February 23, 2023 16:00: Dr. Albert Quintana (Universitat Autònoma de Barcelona), Padova Lecture Series 2023- A pathogen from within: Cellular antiviral responses as a mechanism for neuropathology in mitochondrial diseaseMarch 7, 2023 16:00: Prof. Marianna Patrauchan (Istituto di icrobiologia della Oklahoma University), A Novel Calcium Sensor EfhP Responds to ROS and Controls Iron Uptake in a Human Pathogen P. aeruginosa March 9, 2023 17:00: Dott. Giuseppe Fiermonte 9 Marzo (University of Bari), Mitochondrial Uncoupling Protein 2 (UCP2): a master regulator of cell metabolic reprogramming March 22, 2023 15:00: Prof. Charlotte Helfrich-Förster (Neurobiology and Genetics, Biocentre, Julius-Maximilians University of Wurzburg, Germany), Synchronisation Between Menstrual Cycles and the Luminance and Gravimetric Cycles of the Moon March 23, 2023 17:00, Prof. Patrick Chinnery (University of Cambridge, UK), The Padova Lecture Series 2023- Why does mitochondrial dysfunction target specific cell types?April 20, 2023: Derek Narendra (NINDS-NIH, Bethesda, USA), The Padova Lecture Series 2023- Curbing mitochondrial dysfunction in neurodegeneration: lessons from neurogeneticsApril 17, 2023 15:00: Prof. Angelo D’Alessandro (Director of the Metabolomics Core of the School of Medicine; Director of the Mass Spectrometry Cancer Center Shared Resource - University of Colorado - Anschutz Medical Campus), Small molecules, big data and something in between: High-throughput Metabolomics, towards Personalized Transfusion Medicine May 3, 2023 16:30: Dr. Roberto Feuda (Royal Society Research Fellow, Department of Genetics and Genome Biology-University of Leicester, UK) The origin and evolution of monoaminergic neurons May 5, 2023: Nuno Raimundo (Penn State College of Medicine), The Padova Lecture Series 2023- Organelle networks: a mitochondria-centric perspectiveJuly 6, 2023 16:00: Alessandro Prigione (Heinrich-Heine-University, Düsseldorf), The Padova Lecture Series 2023- Pluripotent stem cells and brain organoids for mitochondrial disease researchMay 24, 2023 14:30: Prof. Andreas Daiber (Department/Division: Center for Cardiology - Cardiology 1, Institution: University Medical Center Mainz) Nitric oxide and superoxide – the Yin and Yang of the cardiovascular system June 7, 2023 17:00: Prof. Michela Matteoli (CNR Institute of Neuroscience and Humanitas Research Hospital), How the immune system affects the synapse June 16, 2023 12:00: Dr Elena Monti (Post Doctoral Research Scholar at Helen Blau's Laboratory, Department of Microbiology and Immunology, Faculty of Medicine, University of Stanford, USA) Targeting 15-PGDH to promote muscle rejuvenation June 22, 2023 16:00: Prof. David Bishop (Institute for Health and Sport (iHeS), Victoria University, Australia), Divergent whole-muscle and fibre-type-specific mitochondrial remodelling to different exercise intensities in humans June 26, 2023 16:30: Prof. Pietro Faccioli (“G. Occhialini“ Department of Physics ,University Milan-Bicocca and INFN Milan) and Prof. Emiliano Biasini (Dipartimento di Biologia Cellulare, Computazionale e Integrata CIBIO, Università di Trento), Functional, pathogenic, and pharmacological roles of protein folding intermediates July 10, 2023, 10:30: Prof. Helen Miranda (State University of Londrina in Brazil), Development of a new human in vitro model to study neuromuscular diseases September 28th, 2023 16:00: Dr. Matteo Bergami (CECAD Research Center, Cologne, Germany), The Padova Lecture Series 2023- Mitochondrial dynamics in neuronal plasticity October 27, 2023: Dr. Luca Peruzzotti-Jametti (University of Cambridge) Metabolic control of myeloid cell function in chronic central nervous system inflammation

Seminars A.Y. 2021-2022

October 27, 2022 17:00: Dr Luca Peruzzotti-Jametti, University of Cambridge
"Metabolic control of myeloid cell function in chronic central nervous system inflammation" flyer TBD

December 9, 2021, 17:00: Prof. Eija Pirinen, Univeristy of Helsinki, Finland, Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation and gut microbiota composition in BMI-discordant twins Download

December 16, 2021, 17:00: Dott. Maya Schuldiner, Weizmann Institute of Sciences, "Staying in touch: Systematic identification of contact site tethers and residents uncovers molecular machinery for a contact between mitochondria and the nucleus in yeast" Download

February 24, 2022 17:00: Dott.ssa Nicoletta Pedemonte, U.O.C. Genetica Medica, IRCCS Istituto Giannina Gaslini "The hunt for new therapies for Cystic Fibrosis" Download

March 10, 2022 17:00 Dr. Michal Minczuk, MRC-MBU, UK,Mitochondrial genome engineering in vivo" Download

March 17, 2022 17:00: Prof. Julien Prudent, University of Cambridge MRC Mitochondrial Biology Unit, Mitochondrial membrane remodelling and mtDNA dynamics Download

April 1, 2022 13:30: Prof. Antonio Zorzano, IRB barcellona, Mitochondrial dynamics: a key influencer of cell inflammation Download

May 5, 2022 17:00: Dr. Paolo Gallipoli, Cancer Research UK Barts Centre, "Mannose metabolism links sugar and fatty acid metabolism in Acute Myeloid Leukaemia and is a novel therapeutic vulnerability" Download

May 19, 2022 17:00: Giampietro Schiavo, UCL Department of Neuromuscular Disease "Therapeutic approaches for hereditary peripheral neuropathy and motor neuron disease" Download

May 25, 2022 11:30am James Sleigh, University College of London, "Restoring axonal transport as a therapeutic strategy in genetic peripheral neuropathy" Download

May 26, 2022 17:00: Dr. Marten Szibor, Jena University Hospital, Germany "Oxygen availability modulates respiratory plasticity in the heart through assembly and disassembly of mitochondrial F1Fo ATPase" Download

June 16, 2022 17:00: Prof. Anthony Moore, University of Sussex, UK , "The role of the alternative oxidase in human health security and the restoration of mitochondrial function." Download

June 20, 2022 16:30: Prof. Douglas Wallace, University of Pennsylvania, Children's Hospital of Philadelphia, "A Mitochondrial Etiology of Common Diseases" Download

June 30, 2022 17:00: Prof. Alexis Jourdain, University of Lausanne, Switzerland, "Functional Genomics Approaches to Mitochondrial Function" Download

July 19, 2022 17:00: Dr. Laura Gasparini Scientific Director - Tau Pathobiology Area Leader @ AbbVie, "Unravelling Tau pathobiology to inform drug discovery of disease modifying approaches for Alzheimer disease" Download

July 25, 2022 16:00 Prof. Michael S. Cohen,Department of Chemical Physiology & Biochemistry-Oregon Health & Science University, "Chemistry-based strategies for investigating NAD+ signaling and protein ADP-ribosylation" Download

September 29, 2022 17:00: Dr. Paolo Gallipoli, Cancer Research UK Barts Centre, "Mannose metabolism links sugar and fatty acid metabolism in Acute Myeloid Leukaemia and is a novel therapeutic vulnerability" Download

October 4, 2022 17:00: Dott.ssa Cristina Ugalde, Instituto de Investigación Hospital 12 de Octubre, Madrid-Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), "Structural heterogeneity of the human respiratory chain" Download

Seminars A.Y. 2020-2021

October 16, 2020, 12:00 pm: Dania Vecchia, IIT-Istituto Italiano di Tecnologia, "Temporal Sharpening of Sensory Responses by Layer 5 in the Mouse Primary Somatosensory Cortex" Download

October 21, 2020, 16:00: Wieland B. Huttner, Max Planck Institute for Molecular Cell Biology and Genetics Dresden, Germany, "Neural stem cells, human-specific genes, and neocortex expansion in development and human evolution" Download

December 9, 2020, 17:00: Letizia Mariotti, MRC Laboratory of Molecular Biology,"A genetically identified class of premotor neurons coding for head movements in the Superior Colliculus" Download

February 3, 2021, 17:00: L. Federico Rossi, PhD, Research Associate, CortexLab, University College London, UK, "Spatial connectivity matches direction selectivity in visual cortex" Download

February 24, 2021, 17:00: Prof. Thomas Simmen, University of Alberta, Canada,"ROS Control of ER-Mitochondria Tethering and Ca2+ Flux" Download

March 18, 2021, 17:00: Prof. Abigail Mackey, University of Copenhagen, "Key Components of Human Myofibre Denervation and Neuromuscular Junction Stability are Modulated by Age and Exercise" Download

March 25, 2021, 17:00: Prof. Harm Kampinga, University of Groningen, Netherlands, "Protein quality control and chaperones" Download

April 15, 2021, 17:00: Prof. Maurício Krause, Instituto de Ciências Básicas da Saúde, "The role of Heat Shock proteins in disease and exercise" Download

April 22, 2021, 17:00: Prof. Erika Fernandez Vizarra, University of Glasgow, "Respiratory chain supercomplexes in human mitochondria" Download

April 29, 2021, 17:00: Prof. Alex Toker, Harvard Medical School, "Discovery, Mechanisms and Therapeutic Targeting of the PI3-Kinase/AKT Pathway in Cancer" Download

May 6, 2021, 16:00: Prof. Andrea Mattevi, University of Pavia, "Structure and mechanisms of ROS generation in NADPH oxidases" Download

May 6, 2021, 17:00: Prof. Karl-Heinz Krause, Faculty of Medicine University of Geneva Switzerland "NADPH oxidase NOX2 in the brain: from neuroregeneration to brain aging" Download

May 13, 2021, 12:00: Prof. Elena Rugarli, Univeristy of Cologne, "CLUH and the post-transcriptional control of mitochondrial function" Download

May 27, 2021, 13:00: Prof. Julio Cárdenas Matus, University of Chile, Title "Role of InsP3R-calcium signal in migration and invasion of cancer cells; new perspectives" Download

June 24, 2021, 17:00: Prof. Stefano Pluchino, Univeristy of Cambridge, "Regenerative Neuroimmunology: a stem cell perspective" Download

September 16, 2021, 17:00: Prof. Dr Edward Chouchani, Department of Cancer Biology, Dana-Farber Cancer Institute, Title "Mechanisms of metabolite regulation over health and disease" Download

Seminars A.Y. 2019-2020

The following seminars have been held in Complesso Vallisneri before the COVID-19 pandemic:

November 6. 2019: Pascale Cossart–InstitutPasteur, Paris, France
November 27, 2019: Fred Bradke–German NeurodegenerativeDiseases Center, Bonn, Germany
November 13, 2019: Dario Alessi–MRC Protein Phosphorylation Unit, University of Dundee, UK
December 18, 2019: Ana Mª Cuervo–Albert Einstein College of Medicine, New York, USA
February 20, 2020: Giuseppe Filomeni- Università degli Studi di Roma "Tor Vergata"; Danish Cancer Society Research Center of Copenaghen

Due to limitations imposed by the pandemic, the PhD School has organized a series of seminars via Zoom ("Webinars"), see the list below and come back often for updates!

May 15, 2020, 4:30 PM: Giampietro Schiavo, UCL Queen Square Institute of Neurology, London, "The role of axonal transport in neurodegenerative diseases"
Juny 22, 2020, 5:00 PM: Enrico Zampese, Laboratory of D. James Surmeier, Department of Physiology, Northwestern University, Chicago, USA, "Calcium, bioenergetics and oxidant stress in SNc DAergic neurons"
July 6, 2020, 4:30 PM: Fabiana Perocchi, Helmholtz Zentrum München, "Functional Genomics of Mitochondrial Physiology and Pathophysiology”
September, date and hour will follow: Aldebaran Hofer, Harvard Medical School, Boston, “cAMP signaling in the cilio”
September 4, 2020, 4:30 pm: Marco Sciacovelli, MRC Cancer Unit, Hutchison MRC Research Centre, University of Cambridge, "The metabolic landscape of renal cancer progression"

The following seminars have been held in Complesso Vallisneri before the COVID-19 pandemic:

November 6. 2019: Pascale Cossart–InstitutPasteur, Paris, France

November 27, 2019: Fred Bradke–German NeurodegenerativeDiseases Center, Bonn, Germany

November 13, 2019: Dario Alessi–MRC Protein Phosphorylation Unit, University of Dundee, UK

December 18, 2019: Ana Mª Cuervo–Albert Einstein College of Medicine, New York, USA

February 20, 2020: Giuseppe Filomeni- Università degli Studi di Roma "Tor Vergata"; Danish Cancer Society Research Center of Copenaghen

Due to limitations imposed by the pandemic, the PhD School has organized a series of seminars via Zoom ("Webinars"), see the list below and come back often for updates!

May 15, 2020, 4:30 PM: Giampietro Schiavo, UCL Queen Square Institute of Neurology, London, "The role of axonal transport in neurodegenerative diseases"

Juny 22, 2020, 5:00 PM: Enrico Zampese, Laboratory of D. James Surmeier, Department of Physiology, Northwestern University, Chicago, USA, "Calcium, bioenergetics and oxidant stress in SNc DAergic neurons"

July 6, 2020, 4:30 PM: Fabiana Perocchi, Helmholtz Zentrum München, "Functional Genomics of Mitochondrial Physiology and Pathophysiology”

September, date and hour will follow: Aldebaran Hofer, Harvard Medical School, Boston, “cAMP signaling in the cilio”

September 4, 2020, 4:30 pm: Marco Sciacovelli, MRC Cancer Unit, Hutchison MRC Research Centre, University of Cambridge, "The metabolic landscape of renal cancer progression"