PhD Courses
All PhD courses are conducted 'in person' and are delivered in English.
Science Communication
| Teacher in charge: Elisabetta Mutto Accordi | 
| Teaching Hours: 13 | 
| Number of ECTS credits allocated: 1 | 
| Course period: January: 27, 16:00-18.00 RL room | 28, 16:00-18.00 RM room | 29, 16:00-18.00 RL room February: 4, 15:00-18.10 RL room | 5, 16:00-17.30 RL room | 11, 15:00-18.10 RL room | 12, 16:00-17.30 RL room | 17, 15:00-18.10 RL room | 21, 16:00-18.10 RL room | 
Course unit contents
Science communication - Communication process - Content selection - Storytelling - Persona Branding - Written communication - Public speaking – PowerPoint presentations
The course is dedicated to students of the 3rd year and secondly to students of 2nd year.
course syllabus
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Nanomedicine: from dream to applications?
| Teacher in charge: Regina Tavano, Emanuele Papini, Giulio Fracasso, Laura Fusco | 
| Teaching Hours: 10 | 
| Number of ECTS credits allocated: 2 | 
| Course period: April 28-29-30 | May 5, 15.30-18.00 RL room | 
Course unit contents
The course includes the following lessons:
- Introduction to Nanotechnology: why is something so small so big? What are the challenges of implementing nanomedicine?
- Surface-masking, protein-corona, biodistribution; how to integrate preclinical models and humans?
- Therapeutic applications (i.e. drug transporter, photodynamic therapy, photothermal ablation)
- Biocompatibility and biomedical applications of new two-dimensional nanomaterials: MXenes
A journey with the cytotoxic lymphocytes
| Teacher in charge: Denis Martinvalet | 
| Teaching Hours: 10 | 
| Number of ECTS credits allocated: 2 | 
| Course period: May 23-26-27-28-30 | 
Course unit contents
The course includes the following lessons:
- Self and non-self for the cytotoxic lymphocytes: A general introduction to basic immunology;
- Cytotoxic lymphocytes in the body: Histology of lymphoid tissues;
- Development, function and pathology of cytotoxic lymphocytes;
- Mechanisms of lymphocyte cytotoxicity. 5. Cytotoxic lymphocytes in the clinic.
Notes for statistical data analyses
| Teacher in charge: Federico Ferraccioli | 
| Teaching Hours: 20 | 
| Number of ECTS credits allocated: 3 | 
| Course period: January 15-16-17-28-29, 9:00-12:00 | 
Course unit contents
- Statistical inference: hypothesis testing, interpretation of p-value, types of errors, power. Confidence intervals. The problem of multiple tests;
- Basic methods: inference on proportions and means, comparisons of two or more samples. Non-parametric alternatives (Wilcoxon, Kruskall-Wallis);
- Advanced methods: One-way or two-way analysis of variance. Introduction to regression models. Introduction to principal component analysis.
The little brain in the heart: journey through the cardiac nervous circuits
| Teacher in charge: Tania Zaglia, Marco Mongillo | 
| Teaching Hours: 10 | 
| Number of ECTS credits allocated: 2 | 
| Course period: March-April 2025 | 
Course unit contents
The course includes the following lessons:
- Vegetative neuro-modulation of the heart;
- Unveiling previously neglected roles of the cardiac autonomic nervous system: a leap from traditional physiology;
- The optogenetics era: a light touch to reveal the deep and dark secrets of cardiac innervation;
- Tissue clearing: an innovative methodology to clear the cardiac nervous tangles 5. Can artificial intelligence predict the thoughts of little heart brain?
Astrocytes at the center of the brain of neurons
| Teacher in charge: To be defined | 
| Teaching Hours: 10 | 
| Number of ECTS credits allocated: 2 | 
| Course period: May 12, 16:00-18:00 RL room | 13, 16:00-18:00 RL room | 14, 16:00-18:00 RL room | 16, 16:00-18:00 RL room | 19, 16:00-18:00 RL room | 
Course unit contents
The course includes the following lessons:
- Introduction to astrocytes, general aspects and brief history;
- Changing the flow: astrocytes and neurovascular coupling
- Astrocytes: from calcium signaling to behavior;
- Astrocytes and anxiety-like behavior;
- The dark side: astrocytes in neuroinflammation and neurodegeneration.
The world of RNA: from cell biology to personalized medicine
| Teacher in charge: Rosario Rizzuto, Annamaria Lia | 
| Teaching Hours: 10 | 
| Number of ECTS credits allocated: 2 | 
| Course period: June 3, 16:00-18:00 RL room | 4, 16:00-18:00 RL room | 6, 16:00-18:00 RL room | 10, 16:00-18:00 RL room | 11, 16:00-18:00 RL room | 
Course unit contents
- Introduction to the world of RNA;
- RNA Delivery: strategies and limitations;
- mRNA based strategies: applications;
- RNA interference and ASOs;
- siRNA: advantages and examples.
Skeletal muscle atrophy: from signaling pathways to the emerging role of lysosomal signaling in physiology and disease
| Teacher in charge: To be defined | 
| Teaching Hours: 10 | 
| Number of ECTS credits allocated: 2 | 
| Course period: June 16, 16:00-18:00 RL room | 17, 16:00-18:00 RL room | 23, 16:00-18:00 RL room | 24, 16:00-18:00 RL room | 25, 16:00-18:00 RL room | 
Course unit contents
The course includes the following lessons:
- Skeletal muscle: introduction to tissue complexity;
- Signaling pathways controlling muscle mass;
- Lysosomes biology: from early discoveries to novel emerging functions;
- Lysosomes biology: from trash bins to signaling hubs;
- Novel insights into lysosomal function in muscle atrophy.
 
           
             
                
